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CD38 inhibitor 1
CAS No. 1700637-55-3
CD38 inhibitor 1( —— )
Catalog No. M23764 CAS No. 1700637-55-3
CD38 inhibitor 1 is an inhibitor of CD38. For hCD38 and mouse CD38, the IC50s are 7.3 nM and 1.9 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 110 | In Stock |
|
| 10MG | 192 | In Stock |
|
| 25MG | 385 | In Stock |
|
| 50MG | 575 | In Stock |
|
| 100MG | 801 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameCD38 inhibitor 1
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NoteResearch use only, not for human use.
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Brief DescriptionCD38 inhibitor 1 is an inhibitor of CD38. For hCD38 and mouse CD38, the IC50s are 7.3 nM and 1.9 nM.
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DescriptionCD38 inhibitor 1 is an inhibitor of CD38. For hCD38 and mouse CD38, the IC50s are 7.3 nM and 1.9 nM.
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In Vitro——
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In VivoCD38 inhibitor (30 mg/kg; oral administration; 2 and 6 hours) significantly elevates NAD levels in liver and muscle. Animal Model:Diet induced obese (DIO) C57Bl6 miceDosage:30 mg/kg Administration:Orally onceResult:NAD levels were significantly increased at both the 2 and 6 h time points in liver and muscle.
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorCD38
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Research Area——
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Indication——
Chemical Information
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CAS Number1700637-55-3
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Formula Weight413.53
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Molecular FormulaC22H27N3O3S
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Purity>98% (HPLC)
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SolubilityDMSO:35.71 mg/mL (86.35 mM; Need ultrasonic)
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SMILESCN(c(ccc(-c1cncs1)c1)c1C(NC(CC1)CCC1OCCOC)=C1)C1=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Haffner CD, et al. Discovery, Synthesis, and Biological Evaluation of Thiazoloquin(az)olin(on)es as Potent CD38 Inhibitors. J Med Chem. 2015 Apr 23;58(8):3548-71.
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